FAQ - Revision history

Geroscientist: /* Which billionaires are funding longevity biotechnology? */

2024-07-09T06:00:05Z

Which billionaires are funding longevity biotechnology?

← Older revision		Revision as of 06:00, 9 July 2024
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	Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:		Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:
	* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />		* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />
	* [[Sam Altman]], CEO of OpenAI, invested [[$180 million ~~into RetroBiosciences\|~~$180 million into RetroBiosciences whose goal is to add]] 10 years to healthy human lifespan.<ref>MIT Technology Review. 2023. Sam Altman invested $180 million into a company trying to delay death. [online] Available at: <https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/> [Accessed 09 July 2024].</ref>		* [[wikipedia:Sam_Altman\|Sam Altman]], CEO of OpenAI, invested [https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/ $180 million into RetroBiosciences whose goal is to add] 10 years to healthy human lifespan.<ref>MIT Technology Review. 2023. Sam Altman invested $180 million into a company trying to delay death. [online] Available at: <https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/> [Accessed 09 July 2024].</ref>
	* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>		* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>
	* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>		* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>

Geroscientist: /* Which billionaires are funding longevity biotechnology? */

2024-07-09T05:58:41Z

Which billionaires are funding longevity biotechnology?

← Older revision		Revision as of 05:58, 9 July 2024
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	Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:		Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:
	* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />		* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />
			* [[Sam Altman]], CEO of OpenAI, invested [[$180 million into RetroBiosciences\|$180 million into RetroBiosciences whose goal is to add]] 10 years to healthy human lifespan.<ref>MIT Technology Review. 2023. Sam Altman invested $180 million into a company trying to delay death. [online] Available at: <https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/> [Accessed 09 July 2024].</ref>
	* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>		* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>
	* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>		* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>

Dmitry Dzhagarov: /* Can healthy lifespan be extended? */

2022-12-05T10:32:41Z

Can healthy lifespan be extended?

← Older revision		Revision as of 10:32, 5 December 2022
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	In animal models, slowing the aging process in animals can be achieved via manipulation of diet, environment, genetics, epigenetics, or with drugs. In mice, over 100 drugs have been shown to extend healthy lifespan by up to 30%.<ref name=":1" /><ref name=":27" />		In animal models, slowing the aging process in animals can be achieved via manipulation of diet, environment, genetics, epigenetics, or with drugs. In mice, over 100 drugs have been shown to extend healthy lifespan by up to 30%.<ref name=":1" /><ref name=":27" />

	The effect of longevity drugs on mice is often significant, delaying or eliminating the burden of age-related problems such as frailty, cataracts, cancer, and sarcopenia. For example, a new class of drugs called senolytics have been shown to extend healthy lifespan in mice by over 30% whilst delaying age-related dysfunction.		The effect of longevity drugs on mice is often significant, delaying or eliminating the burden of age-related problems such as [[frailty]], cataracts, cancer, and sarcopenia. For example, a new class of drugs called senolytics have been shown to extend healthy lifespan in mice by over 30% whilst delaying age-related dysfunction.

	== Which therapies may extend healthy lifespan? ==		== Which therapies may extend healthy lifespan? ==

Geroscientist: /* Will anti-aging drugs only be available to the rich? */

2022-01-26T10:34:20Z

Will anti-aging drugs only be available to the rich?

← Older revision		Revision as of 10:34, 26 January 2022
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	A common objection to the development of longevity technologies is that they may lead to an unsustainably large population size.		A common objection to the development of longevity technologies is that they may lead to an unsustainably large population size.

	One study of a 2005 Swedish cohort of 9 million people modeled the effect of various anti-aging scenarios. The researchers showed that even with the most radical life-extension technology in which aging completely stopped after age 60, the population growth across 100 years was only 22%.<ref>Gavrilov, L. A., & Gavrilova, N. S. (2010). Demographic consequences of defeating aging. ''Rejuvenation research'', ''13''(2-3), 329-334.</ref>		One study of a 2005 Swedish cohort of 9 million people modeled the effect of various anti-aging scenarios. The researchers showed that even with the most radical life-extension technology in which aging completely stopped after age 60, the population growth across 100 years was only 22%.<ref>Gavrilov, L. A., & Gavrilova, N. S. (2010). Demographic consequences of defeating aging. ''Rejuvenation research'', ''13''(2-3), 329-334.</ref> In reality, the first aging drugs will likely slow aging by a modest amount, and most likely increase healthspan as opposed to lifespan. This is partly based on evidence in animals showing that it is easier to extend median, as opposed to maximal lifespan.

	Currently, the world’s population is 7.9 billion, and the WHO predicts the population will peak at 11 billion in 2100 before falling due to declining birth rates in many parts of the world. The fastest growing populations are in Africa and South-east Asia. However, several factors are thought to reduce birth rates over time, including increased access to contraceptives, female empowerment, increased education and increased employment. There is evidence that populations that move to a more advanced economy show a reduction in birth rates. This is expected to mitigate the increase in population size from longer lifespans.		Currently, the world’s population is 7.9 billion, and the WHO predicts the population will peak at 11 billion in 2100 before falling due to declining birth rates in many parts of the world. The fastest growing populations are in Africa and South-east Asia. However, several factors are thought to reduce birth rates over time, including increased access to contraceptives, female empowerment, increased education and increased employment. There is evidence that populations that move to a more advanced economy show a reduction in birth rates. This is expected to mitigate the increase in population size from longer lifespans.

Geroscientist: /* Will anti-aging technology lead to overpopulation? */

2022-01-26T10:23:54Z

Will anti-aging technology lead to overpopulation?

← Older revision		Revision as of 10:23, 26 January 2022
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	Another large clinical trial is the Participitory Evaluation (of) Aging (with) Rapamycin (for) Longevity (PEARL) study. The goal of this study is to determine whether rapamycin, a drug currently approved for immunosuppression during organ transplants, slows biomarkers of aging in 1000 adults. The PEARL trial is being run by AgelessRx.<ref name=":15" />		Another large clinical trial is the Participitory Evaluation (of) Aging (with) Rapamycin (for) Longevity (PEARL) study. The goal of this study is to determine whether rapamycin, a drug currently approved for immunosuppression during organ transplants, slows biomarkers of aging in 1000 adults. The PEARL trial is being run by AgelessRx.<ref name=":15" />
	== Is aging a natural process that should be accepted? ==		== Is aging a natural process that should be accepted? ==
	Although aging is a natural process in humans, it is the driving force of many diseases such as cancer and Alzheimer's disease - which as a society we have decided are worth trying to find cures for. In the past, these conditions, as well as atherosclerosis and even infectious diseases were once thought of as natural processes ~~that could not~~ be ~~treated~~. ~~However~~, ~~nowadays it is understood that they are diseases that can be treated~~.		Although aging is a natural process in humans, it is the driving force of many diseases such as cancer and Alzheimer's disease - which as a society we have decided are worth trying to find cures for. In the past, these conditions, as well as atherosclerosis and even infectious diseases were once thought of as natural processes to be accepted. As treatments for previously untreatable diseases started being developed, society moved to accommodate this.

	Atherosclerosis, the hardening of the arteries, was once viewed as a natural process that was simply a consequence of aging. However, when treatments such as statins were later developed to prevent atherosclerosis, ~~the disease~~ became widely regarded as a disease to be cured. Statins are now one one of the most widely prescribed drugs in the world, used in preventing heart diseases. The inventor of statins, Akira Endo, describes in his historical paper: “Serious research on the role of cholesterol in human atherosclerosis did not really get underway until the 1940s, due to a prevailing view that the disease was a simple consequence of aging and could not be prevented.”<ref>Endo A. (2010). A historical perspective on the discovery of statins. ''Proceedings of the Japan Academy. Series B, Physical and biological sciences'', ''86''(5), 484–493. <nowiki>https://doi.org/10.2183/pjab.86.484</nowiki></ref>		Atherosclerosis, the hardening of the arteries, was once viewed as a natural process that was simply a consequence of aging. However, when treatments such as statins were later developed to prevent atherosclerosis, it became widely regarded as a disease to be cured. Statins are now one one of the most widely prescribed drugs in the world, used in preventing heart diseases. The inventor of statins, Akira Endo, describes in his historical paper: “Serious research on the role of cholesterol in human atherosclerosis did not really get underway until the 1940s, due to a prevailing view that the disease was a simple consequence of aging and could not be prevented.”<ref>Endo A. (2010). A historical perspective on the discovery of statins. ''Proceedings of the Japan Academy. Series B, Physical and biological sciences'', ''86''(5), 484–493. <nowiki>https://doi.org/10.2183/pjab.86.484</nowiki></ref>

	== Will anti-aging technology lead to overpopulation? ==		== Will anti-aging technology lead to overpopulation? ==

Geroscientist: /* Do all animals age in the same way? */

2022-01-26T09:07:37Z

Do all animals age in the same way?

← Older revision		Revision as of 09:07, 26 January 2022
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	== What are the economic benefits of extending healthy lifespan? ==		== What are the economic benefits of extending healthy lifespan? ==
	Extending the healthy human lifespan could have significant economic benefits gobally. An economic analysis from 2021 by researchers at the University of Oxford and Harvard University estimated the benefit of a drug that slows aging by 1 year as $38 trillion.<ref name=":23">Scott, A. J., Ellison, M., & Sinclair, D. A. (2021). The economic value of targeting aging. ''Nature Aging'', ''1''(7), 616-623.</ref> This is ~~primarily~~ because slowing aging ~~reduces the incidence of~~ age-related diseases such as cancer and Alzheimer’s disease, which ~~require expensive treatment approaches~~. The study demonstrated a larger economic benefit of slowing aging than curing the individual diseases of aging. <ref name=":23" />		Extending the healthy human lifespan could have significant economic benefits gobally. An economic analysis from 2021 by researchers at the University of Oxford and Harvard University estimated the benefit of a drug that slows aging by 1 year as $38 trillion.<ref name=":23">Scott, A. J., Ellison, M., & Sinclair, D. A. (2021). The economic value of targeting aging. ''Nature Aging'', ''1''(7), 616-623.</ref> This is mainly because slowing aging prevents age-related diseases such as cancer and Alzheimer’s disease, which are of great expense to healthcare systems, productivity, and society. The study demonstrated a larger economic benefit of slowing aging than curing the individual diseases of aging. <ref name=":23" />
	== Which scientists and institutions are trying to understand and reverse aging? ==		== Which scientists and institutions are trying to understand and reverse aging? ==
	Over [https://whoswho.senescence.info/ 300 scientists are working on understanding the biology of aging] in leading institutions that include Harvard University, Stanford University, Yale University, and the University of Oxford.<ref>''Who's Who in Gerontology: Researchers and Companies Working on Aging''. (n.d.). Who's Who in Gerontology: Researchers and Companies Working on Aging. <nowiki>https://whoswho.senescence.info/</nowiki></ref> Some of the most well-known institutes and labs include:		Over [https://whoswho.senescence.info/ 300 scientists are working on understanding the biology of aging] in leading institutions that include Harvard University, Stanford University, Yale University, and the University of Oxford.<ref>''Who's Who in Gerontology: Researchers and Companies Working on Aging''. (n.d.). Who's Who in Gerontology: Researchers and Companies Working on Aging. <nowiki>https://whoswho.senescence.info/</nowiki></ref> Some of the most well-known institutes and labs include:

Geroscientist: /* How is aging biology research different to other fields of medical research? */

2022-01-26T09:03:48Z

How is aging biology research different to other fields of medical research?

← Older revision		Revision as of 09:03, 26 January 2022
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	== Do all animals age in the same way? ==		== Do all animals age in the same way? ==
	[[File:Naked mole rat graph.png\|alt=Naked mole rat graph\|thumb\|530x530px\|The naked mole-rat does not follow the same increased risk of mortality due to aging that humans and other mammals do.<ref>Ruby, J. G., Smith, M., & Buffenstein, R. (2018). Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age. ''elife'', ''7'', e31157.</ref> ]]		[[File:Naked mole rat graph.png\|alt=Naked mole rat graph\|thumb\|530x530px\|The naked mole-rat does not follow the same increased risk of mortality due to aging that humans and other mammals do.<ref>Ruby, J. G., Smith, M., & Buffenstein, R. (2018). Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age. ''elife'', ''7'', e31157.</ref> ]]
	Many species, due to differences in their biology, age at different rates to humans. The jellyfish ''Turritopsis dohrnii'' can revert to earlier stages of its life cycle in response to stress, and ~~can~~ theoretically ~~live forever~~ - though eventually dies, usually due to predation.<ref>Bavestrello, Giorgio; Christian Sommer; Michele Sarà (1992). "Bi-directional conversion in Turritopsis nutricula (Hydrozoa)".</ref>		Many species, due to differences in their biology, age at different rates to humans. The jellyfish ''Turritopsis dohrnii'' can revert to earlier stages of its life cycle in response to stress, and is theoretically ''biologically'' immortal - though eventually dies, usually due to predation.<ref>Bavestrello, Giorgio; Christian Sommer; Michele Sarà (1992). "Bi-directional conversion in Turritopsis nutricula (Hydrozoa)".</ref>

	Among mammals, the naked mole rat is an exceptionally long lived organism ~~that~~ lives roughly ten times longer than similarly-sized rats.<ref name=":3">Ruby, J. G., Smith, M., & Buffenstein, R. (2018). Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age. ''elife'', ''7'', e31157.</ref><ref>Buffenstein, R., Amoroso, V., Andziak, B., Avdieiev, S., Azpurua, J., Barker, A. J., ... & Smith, E. S. J. (2021). The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology. ''Biological Reviews''.</ref> Unlike other organisms, such as humans, horses and mice, the mortality rate of the naked mole rat appears steady over time. This trend does not follow the exponential increase in mortality (Gompertz-Makeham law) that humans do.<ref name=":3" />		Among mammals, the naked mole rat is an exceptionally long lived organism. It lives roughly ten times longer than similarly-sized rats, with resistance to cancer and age-related diseases.<ref name=":3">Ruby, J. G., Smith, M., & Buffenstein, R. (2018). Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age. ''elife'', ''7'', e31157.</ref><ref>Buffenstein, R., Amoroso, V., Andziak, B., Avdieiev, S., Azpurua, J., Barker, A. J., ... & Smith, E. S. J. (2021). The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology. ''Biological Reviews''.</ref> Unlike other organisms, such as humans, horses and mice, the mortality rate of the naked mole rat appears steady over time. This trend does not follow the exponential increase in mortality (Gompertz-Makeham law) that humans do.<ref name=":3" />

	Scientists are now studying the naked mole rat to identify key patterns in their genetics, environmental traits, and metabolism that may be responsible for their longer lifespans.<ref>Kim, E. B., Fang, X., Fushan, A. A., Huang, Z., Lobanov, A. V., Han, L., ... & Gladyshev, V. N. (2011). Genome sequencing reveals insights into physiology and longevity of the naked mole rat. ''Nature'', ''479''(7372), 223-227.</ref>		Scientists are now studying the naked mole rat to identify key patterns in their genetics, environmental traits, and metabolism that may be responsible for their longer lifespans.<ref>Kim, E. B., Fang, X., Fushan, A. A., Huang, Z., Lobanov, A. V., Han, L., ... & Gladyshev, V. N. (2011). Genome sequencing reveals insights into physiology and longevity of the naked mole rat. ''Nature'', ''479''(7372), 223-227.</ref>

Geroscientist: /* Which companies are trying to solve aging? */

2022-01-26T08:38:34Z

Which companies are trying to solve aging?

← Older revision		Revision as of 08:38, 26 January 2022
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	Aging is not currently classified as a disease by regulatory bodies such as the Food and Drug Administration (FDA) in the United States. However, several scientists in the aging field have publicly stated their preference for aging to be defined as, or at least thought of, as a disease, including professors David Sinclair and Nir Barzilai.<ref>TEDx Talks. (2020, June 9). ''Ageing'' ''is'' ''a'' ''treatable'' ''disease'' ''\|'' ''Nir'' ''Bazilai'' ''\|'' ''TEDxBeaconStreetSalon'' [Video]. YouTube. <nowiki>https://www.youtube.com/watch?v=XN7rLbCBO1c</nowiki></ref>		Aging is not currently classified as a disease by regulatory bodies such as the Food and Drug Administration (FDA) in the United States. However, several scientists in the aging field have publicly stated their preference for aging to be defined as, or at least thought of, as a disease, including professors David Sinclair and Nir Barzilai.<ref>TEDx Talks. (2020, June 9). ''Ageing'' ''is'' ''a'' ''treatable'' ''disease'' ''\|'' ''Nir'' ''Bazilai'' ''\|'' ''TEDxBeaconStreetSalon'' [Video]. YouTube. <nowiki>https://www.youtube.com/watch?v=XN7rLbCBO1c</nowiki></ref>

	~~The 1st recognition by the WHO~~ of aging as a treatable medical condition ~~came~~ from the new ICD-11 extension code MG2A. ~~This code,~~ “Ageing associated decline in intrinsic capacity”, is classified under "general symptoms". ~~In addition, the~~ XT9T ~~code~~ "Ageing-related” under the "Causality" category recognizes aging as a contributor to disease.		Recognition of aging as a treatable medical condition by the WHO comes from the new ICD-11 extension code MG2A and XT9T. MG2A refers to “Ageing associated decline in intrinsic capacity”, and is classified under "general symptoms".<ref>https://icd.who.int/dev11/l-m/en?fbclid=IwAR22C-Gx2i9mckSYLenAwLAkWuBt3s3ncQLdjs5aar1W42jAbibuD6SQ2gE#/http://id.who.int/icd/entity/835503193</ref> XT9T refers to "Ageing-related”, under the "Causality" category, and recognizes aging as a contributor to disease.<ref>https://icd.who.int/browse11/l-m/en#/http%3a%2f%2fid.who.int%2ficd%2fentity%2f459275392</ref>

	== What are the economic benefits of extending healthy lifespan? ==		== What are the economic benefits of extending healthy lifespan? ==

Geroscientist: /* Multi-omic clocks */

2022-01-26T07:49:52Z

Multi-omic clocks

← Older revision		Revision as of 07:49, 26 January 2022
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	== Is aging considered a disease? ==		== Is aging considered a disease? ==
	Aging is not currently classified as a disease by regulatory bodies such as the Food and Drug Administration (FDA) in the United States. However, several scientists in the aging field have publicly stated their preference for aging to be defined as, or at least thought of, as a disease, including professors David Sinclair and Nir Barzilai.<ref>TEDx Talks. (2020, June 9). ''Ageing'' ''is'' ''a'' ''treatable'' ''disease'' ''\|'' ''Nir'' ''Bazilai'' ''\|'' ''TEDxBeaconStreetSalon'' [Video]. YouTube. <nowiki>https://www.youtube.com/watch?v=XN7rLbCBO1c</nowiki></ref>		Aging is not currently classified as a disease by regulatory bodies such as the Food and Drug Administration (FDA) in the United States. However, several scientists in the aging field have publicly stated their preference for aging to be defined as, or at least thought of, as a disease, including professors David Sinclair and Nir Barzilai.<ref>TEDx Talks. (2020, June 9). ''Ageing'' ''is'' ''a'' ''treatable'' ''disease'' ''\|'' ''Nir'' ''Bazilai'' ''\|'' ''TEDxBeaconStreetSalon'' [Video]. YouTube. <nowiki>https://www.youtube.com/watch?v=XN7rLbCBO1c</nowiki></ref>

			The 1st recognition by the WHO of aging as a treatable medical condition came from the new ICD-11 extension code MG2A. This code, “Ageing associated decline in intrinsic capacity”, is classified under "general symptoms". In addition, the XT9T code "Ageing-related” under the "Causality" category recognizes aging as a contributor to disease.

	== What are the economic benefits of extending healthy lifespan? ==		== What are the economic benefits of extending healthy lifespan? ==

Geroscientist: /* Multi-omic clocks */

2022-01-26T07:10:10Z

Multi-omic clocks

← Older revision		Revision as of 07:10, 26 January 2022
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	== Is aging considered a disease? ==		== Is aging considered a disease? ==
	Aging is not currently classified as a disease by regulatory bodies such as the Food and Drug Administration (FDA) in the United States. However, several scientists in the aging field have publicly stated their preference for aging to be ~~considered~~ a disease, including ~~professor~~ David Sinclair and ~~professor~~ Nir Barzilai.<ref>TEDx Talks. (2020, June 9). ''Ageing'' ''is'' ''a'' ''treatable'' ''disease'' ''\|'' ''Nir'' ''Bazilai'' ''\|'' ''TEDxBeaconStreetSalon'' [Video]. YouTube. <nowiki>https://www.youtube.com/watch?v=XN7rLbCBO1c</nowiki></ref>		Aging is not currently classified as a disease by regulatory bodies such as the Food and Drug Administration (FDA) in the United States. However, several scientists in the aging field have publicly stated their preference for aging to be defined as, or at least thought of, as a disease, including professors David Sinclair and Nir Barzilai.<ref>TEDx Talks. (2020, June 9). ''Ageing'' ''is'' ''a'' ''treatable'' ''disease'' ''\|'' ''Nir'' ''Bazilai'' ''\|'' ''TEDxBeaconStreetSalon'' [Video]. YouTube. <nowiki>https://www.youtube.com/watch?v=XN7rLbCBO1c</nowiki></ref>

	== What are the economic benefits of extending healthy lifespan? ==		== What are the economic benefits of extending healthy lifespan? ==

← Older revision		Revision as of 06:00, 9 July 2024
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	Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:		Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:
	* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />		* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />
	* [[Sam Altman]], CEO of OpenAI, invested [[$180 million ~~into RetroBiosciences\|~~$180 million into RetroBiosciences whose goal is to add]] 10 years to healthy human lifespan.<ref>MIT Technology Review. 2023. Sam Altman invested $180 million into a company trying to delay death. [online] Available at: <https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/> [Accessed 09 July 2024].</ref>		* [[wikipedia:Sam_Altman\|Sam Altman]], CEO of OpenAI, invested [https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/ $180 million into RetroBiosciences whose goal is to add] 10 years to healthy human lifespan.<ref>MIT Technology Review. 2023. Sam Altman invested $180 million into a company trying to delay death. [online] Available at: <https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/> [Accessed 09 July 2024].</ref>
	* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>		* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>
	* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>		* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>

← Older revision		Revision as of 05:58, 9 July 2024
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	Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:		Several billionaires have funded companies or initiatives to slow or reverse human aging. These include:
	* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />		* [[wikipedia:Jeff_Bezos\|Jeff Bezos]], co-founder of Amazon, helped raise [https://www.technologyreview.com/2021/09/04/1034364/altos-labs-silicon-valleys-jeff-bezos-milner-bet-living-forever/ $3 billion for new anti-aging drug company Altos Labs] in 2021.<ref name=":7" />
			* [[Sam Altman]], CEO of OpenAI, invested [[$180 million into RetroBiosciences\|$180 million into RetroBiosciences whose goal is to add]] 10 years to healthy human lifespan.<ref>MIT Technology Review. 2023. Sam Altman invested $180 million into a company trying to delay death. [online] Available at: <https://www.technologyreview.com/2023/03/08/1069523/sam-altman-investment-180-million-retro-biosciences-longevity-death/> [Accessed 09 July 2024].</ref>
	* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>		* [[wikipedia:Peter_Thiel\|Peter Thiel]], co-founder of PayPal, was an [https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html early investor in Unity Biotechnology].<ref>CNBC. 2021. ''Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging''. [online] Available at: <<nowiki>https://www.cnbc.com/2018/08/29/-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html</nowiki>> [Accessed 15 December 2021].</ref>
	* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>		* [[wikipedia:Sergey_Brin\|Sergey Brin]], co-founder of Google, donated [https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html $25 million for the National Academy of Medicine’s Grand Challenge in Health Longevity] to 'end aging forever'.<ref>Google’s co-founders and other Silicon Valley billionaires are trying to live forever. (2021). Retrieved 15 December 2021, from <nowiki>https://www.cnbc.com/2017/03/31/google-co-founders-and-silicon-valley-billionaires-try-to-live-forever.html</nowiki></ref>