Limb regeneration - Revision history

Geroscientist at 23:24, 28 February 2022

2022-02-28T23:24:04Z

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	In 2022 ~~scientist~~ from Tufts University showed that ~~they could regenerate~~ the hindlimb of ~~an adult African clawed~~ frog ~~(''Xenopus laevis'')~~ after amputation<ref>Murugan, N. J., Vigran, H. J., Miller, K. A., Golding, A. Pham, Q. L., Sperry, M. M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., & Levin, M. (2022). Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis. Science Advances, 8(4), https://doi.org/10.1126/sciadv.abj2164</ref>; something that ~~doesn't~~ happen ~~by itself~~ in nature. They demonstrated 18 months of regrowth of the limb ~~after~~ only 24-hour exposure to a combination of drugs delivered by a wearable bioreactor. The regenerated limb included skin, bone, vasculature and nerves.		In 2022, scientists from Tufts University showed for the first time that regeneration of the hindlimb of a frog after amputation was possible.<ref>Murugan, N. J., Vigran, H. J., Miller, K. A., Golding, A. Pham, Q. L., Sperry, M. M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., & Levin, M. (2022). Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis. Science Advances, 8(4), https://doi.org/10.1126/sciadv.abj2164</ref> This was done in the adult African clawed frog (''Xenopus laevis'') after amputation, something that is not known to happen in nature. They demonstrated 18 months of regrowth of the limb with only 24-hour exposure to a combination of drugs delivered by a wearable bioreactor. The regenerated limb included skin, bone, vasculature and nerves.

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Bogdan at 11:01, 28 February 2022

2022-02-28T11:01:27Z

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Bogdan: Added to stub category

2022-02-28T10:58:53Z

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	In 2022 scientist from Tufts University showed that they could regenerate the hindlimb of an adult African clawed frog (''Xenopus laevis'') after amputation<ref>Murugan, N. J., Vigran, H. J., Miller, K. A., Golding, A. Pham, Q. L., Sperry, M. M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., & Levin, M. (2022). Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis. Science Advances, 8(4), https://doi.org/10.1126/sciadv.abj2164</ref>; something that doesn't happen by itself in nature. They demonstrated 18 months of regrowth of the limb after only 24-hour exposure to a combination of drugs delivered by a wearable bioreactor. The regenerated limb included skin, bone, vasculature and nerves.		In 2022 scientist from Tufts University showed that they could regenerate the hindlimb of an adult African clawed frog (''Xenopus laevis'') after amputation<ref>Murugan, N. J., Vigran, H. J., Miller, K. A., Golding, A. Pham, Q. L., Sperry, M. M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., & Levin, M. (2022). Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis. Science Advances, 8(4), https://doi.org/10.1126/sciadv.abj2164</ref>; something that doesn't happen by itself in nature. They demonstrated 18 months of regrowth of the limb after only 24-hour exposure to a combination of drugs delivered by a wearable bioreactor. The regenerated limb included skin, bone, vasculature and nerves.

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Bogdan: Added to Longevity category

2022-02-28T09:30:55Z

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MarcS: This is the first version of a stub on limb regeneration. A stub is a short article in need of expansion. We could ask the authors of the referenced journal article to expand the stub into a full Wiki article.

2022-02-27T13:25:31Z

This is the first version of a stub on limb regeneration. A stub is a short article in need of expansion. We could ask the authors of the referenced journal article to expand the stub into a full Wiki article.

New page

In 2022 scientist from Tufts University showed that they could regenerate the hindlimb of an adult African clawed frog (''Xenopus laevis'') after amputation<ref>Murugan, N. J., Vigran, H. J., Miller, K. A., Golding, A. Pham, Q. L., Sperry, M. M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., & Levin, M. (2022). Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis. Science Advances, 8(4), https://doi.org/10.1126/sciadv.abj2164</ref>; something that doesn't happen by itself in nature. They demonstrated 18 months of regrowth of the limb after only 24-hour exposure to a combination of drugs delivered by a wearable bioreactor. The regenerated limb included skin, bone, vasculature and nerves.

== References ==
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