Dmitry Dzhagarov: Created page with "'''Longevity quotient (LQ)''' is a simplified measure to enable normalized comparisons of various species' longevity.Palmore, E. (1969). Predicting longevity: A follow-up controlling for age. The Gerontologist, 9(4_Part_1), 247-250. LQ gives an indication of how long a species’ lifespan is compared with other species of similar size, where LQ = observed longevity/expected longevity.Austad, S. N., & Fischer, K. E. (1991). Mammalian aging, metabolism, and..."

2023-10-25T04:37:14Z

Created page with "'''Longevity quotient (LQ)''' is a simplified measure to enable normalized comparisons of various species' longevity.<ref>Palmore, E. (1969). Predicting longevity: A follow-up controlling for age. The Gerontologist, 9(4_Part_1), 247-250.</ref> LQ gives an indication of how long a species’ lifespan is compared with other species of similar size, where LQ = observed longevity/expected longevity.<ref>Austad, S. N., & Fischer, K. E. (1991). Mammalian aging, metabolism, and..."

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'''Longevity quotient (LQ)''' is a simplified measure to enable normalized comparisons of various species' longevity.<ref>Palmore, E. (1969). Predicting longevity: A follow-up controlling for age. The Gerontologist, 9(4_Part_1), 247-250.</ref> LQ gives an indication of how long a species’ lifespan is compared with other species of similar size, where LQ = observed longevity/expected longevity.<ref>Austad, S. N., & Fischer, K. E. (1991). Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials. Journal of gerontology, 46(2), B47-B53. PMID: 1997563 DOI: 10.1093/geronj/46.2.b47</ref> Mean longevity quotient allows to identify of long-lived species.<ref>Yu, Z., Seim, I., Yin, M., Tian, R., Sun, D., Ren, W., ... & Xu, S. (2021). Comparative analyses of aging-related genes in long-lived mammals provide insights into natural longevity. The Innovation, 2(2). PMID: 34557758 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454735/ PMC8454735] DOI: 10.1016/j.xinn.2021.100108</ref>

'''The Longevity Quotient is the ratio of actual maximum species life span (MLSP) to that predicted by body mass'''.<ref>Hulbert, A. J. (2008). Explaining longevity of different animals: is membrane fatty acid composition the missing link?. Age, 30(2-3), 89-97.</ref> It evaluates the manifestation of [[Aging and cancer#Peto's paradox|Peto's paradox]] in its evolutionary interpretation as the ability to grow for a long time and, accordingly, to age for a long time in different animals.<ref>Roche, B., Hochberg, M. E., Caulin, A. F., Maley, C. C., Gatenby, R. A., Misse, D., & Thomas, F. (2012). Natural resistance to cancers: a Darwinian hypothesis to explain Peto’s paradox. BMC cancer, 12(1), 1-4. PMID: 22943484 PMCID: PMC3488527 DOI: 10.1186/1471-2407-12-387</ref><ref>Perillo, M., Silla, A., Punzo, A., Caliceti, C., Kriete, A., Sell, C., & Lorenzini, A. (2023). Peto’s paradox: nature has used multiple strategies to keep cancer at bay while evolving long lifespans and large body masses. A systematic mini-review. Biomedical journal, 100654. PMID: 37604250 [https://doi.org/10.1016/j.bj.2023.100654 DOI: 10.1016/j.bj.2023.100654]</ref>

== References ==
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[[Category:Longevity concepts]]
[[Category:Main list]]
[[Category:Drafts]]
[[Category:Glossary]]

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