Mediterranean diet - Revision history

Dmitry Dzhagarov at 17:30, 19 September 2024

2024-09-19T17:30:04Z

← Older revision		Revision as of 17:30, 19 September 2024
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	The '''Mediterranean diet''' (sometimes referred to as MedDiet) is a diet rich in seafood, fruits, vegetables, whole grains, nuts, cheese and healthy fats, such as olive oil.<ref name="Definition">Davis, C., Bryan, J., Hodgson, J., & Murphy, K. (2015). Definition of the Mediterranean diet: a literature review. Nutrients, 7(11), 9139-9153. PMID: 26556369 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663587 reference] DOI: 10.3390/nu7115459</ref> On average, the MedDiet contains three to nine serves of vegetables, half to two serves of fruit, one to 13 serves of cereals and up to eight serves of olive oil daily. It contains approximately 9300 kJ: 37% as total fat, 18% as monounsaturated and 9% as saturated, and 33g of fibre per day.<ref name="Definition" />		The '''Mediterranean diet''' (sometimes referred to as MedDiet) is a '''diet rich in seafood (fish), beans, fruits, vegetables, whole grains, nuts, cheese and healthy fats, such as olive oil'''.<ref name="Definition">Davis, C., Bryan, J., Hodgson, J., & Murphy, K. (2015). Definition of the Mediterranean diet: a literature review. Nutrients, 7(11), 9139-9153. PMID: 26556369 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663587 reference] DOI: 10.3390/nu7115459</ref> Occasionally also '''a moderate amount of red wine.'''<ref>Willett, W. C., Sacks, F., Trichopoulou, A., Drescher, G., Ferro-Luzzi, A., Helsing, E., & Trichopoulos, D. (1995). Mediterranean diet pyramid: a cultural model for healthy eating. The American journal of clinical nutrition, 61(6), 1402S-1406S.</ref><ref>Sofi, F., Abbate, R., Gensini, G. F., & Casini, A. (2010). Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. The American journal of clinical nutrition, 92(5), 1189-1196.</ref> On average, the MedDiet contains three to nine serves of vegetables, half to two serves of fruit, one to 13 serves of cereals and up to eight serves of olive oil daily. It contains approximately 9300 kJ: 37% as total fat, 18% as monounsaturated and 9% as saturated, and 33g of fibre per day.<ref name="Definition" />

	The majority of studies emphasize the same key dietary components and principles for the benefits associated to the MedDiet: an increased intake of vegetables, wholegrains, and the preferential consumption of white meat as a substitute of red and processed meat, as well as abundant use of olive oil. However, the reporting of specific dietary recommendations for fruit, legumes, nuts, bread, red wine, and fermentable dairy products are generally less consistent or not reported.<ref name="Influence" /><ref>McClure, R., & Villani, A. (2019). Greater adherence to a Mediterranean Diet is associated with better gait speed in older adults with type 2 diabetes mellitus. Clinical nutrition ESPEN, 32, 33-39. PMID: 31221287 DOI:[https://doi.org/10.1016/j.clnesp.2019.05.009 reference]</ref>		The majority of studies emphasize the same key dietary components and principles for the benefits associated to the MedDiet: an increased intake of vegetables, wholegrains, and the preferential consumption of white meat as a substitute of red and processed meat, as well as abundant use of olive oil. However, the reporting of specific dietary recommendations for fruit, legumes, nuts, bread, red wine, and fermentable dairy products are generally less consistent or not reported.<ref name="Influence" /><ref>McClure, R., & Villani, A. (2019). Greater adherence to a Mediterranean Diet is associated with better gait speed in older adults with type 2 diabetes mellitus. Clinical nutrition ESPEN, 32, 33-39. PMID: 31221287 DOI:[https://doi.org/10.1016/j.clnesp.2019.05.009 reference]</ref>
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	Mediterranean diet adherence had, in general, a positive role in muscle mass and muscle function with a lower risk of sarcopenia.<ref>Papadopoulou, S. K., Detopoulou, P., Voulgaridou, G., Tsoumana, D., Spanoudaki, M., Sadikou, F., ... & Nikolaidis, P. (2023). Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review. Nutrients, 15(5), 1104. PMID: 36904104 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005300 reference] DOI: 10.3390/nu15051104</ref><ref>Cacciatore, S., Calvani, R., Marzetti, E., Picca, A., Coelho-Júnior, H. J., Martone, A. M., ... & Landi, F. (2023). Low Adherence to Mediterranean Diet Is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Results from the Longevity Check-Up (Lookup) 7+ Project. Nutrients, 15(4), 1026. PMID: 36839385 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959184 reference] DOI: 10.3390/nu15041026</ref>		Mediterranean diet adherence had, in general, a positive role in muscle mass and muscle function with a lower risk of sarcopenia.<ref>Papadopoulou, S. K., Detopoulou, P., Voulgaridou, G., Tsoumana, D., Spanoudaki, M., Sadikou, F., ... & Nikolaidis, P. (2023). Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review. Nutrients, 15(5), 1104. PMID: 36904104 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005300 reference] DOI: 10.3390/nu15051104</ref><ref>Cacciatore, S., Calvani, R., Marzetti, E., Picca, A., Coelho-Júnior, H. J., Martone, A. M., ... & Landi, F. (2023). Low Adherence to Mediterranean Diet Is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Results from the Longevity Check-Up (Lookup) 7+ Project. Nutrients, 15(4), 1026. PMID: 36839385 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959184 reference] DOI: 10.3390/nu15041026</ref>

			Cardiovascular events and cardiovascular mortality are significantly reduced when associated with the Mediterranean Diet.<ref>Sebastian, S. A., Padda, I., & Johal, G. (2024). Long-Term Impact of Mediterranean Diet on Cardiovascular Disease Prevention: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Current Problems in Cardiology, 102509. PMID: 38431146 DOI: 10.1016/j.cpcardiol.2024.102509</ref><ref>Barbosa, A. R., Pais, S., Marreiros, A., & Correia, M. (2024). Impact of a Mediterranean-Inspired Diet on Cardiovascular Disease Risk Factors: A Randomized Clinical Trial. Nutrients, 16(15), 2443. PMID: 39125324 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11314620/ PMC11314620] DOI: 10.3390/nu16152443</ref>

	Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>		Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>
	Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>		Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>

Dmitry Dzhagarov: /* Olive Oil in the Mediterranean Diet */

2024-01-02T19:32:02Z

Olive Oil in the Mediterranean Diet

← Older revision		Revision as of 19:32, 2 January 2024
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	== Olive Oil in the Mediterranean Diet ==		== Olive Oil in the Mediterranean Diet ==
	One of the most examined oils for its health properties is olive oil, especially extra virgin olive oil (EVOO).<ref>Riolo, R., De Rosa, R., Simonetta, I., & Tuttolomondo, A. (2022). Olive Oil in the Mediterranean Diet and Its Biochemical and Molecular Effects on Cardiovascular Health through an Analysis of Genetics and Epigenetics. International Journal of Molecular Sciences, 23(24), 16002. PMID: 36555645 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782563 reference] DOI: 10.3390/ijms232416002</ref><ref>Fernández del Río, L., Gutiérrez-Casado, E., Varela-López, A., & Villalba, J. M. (2016). Olive oil and the hallmarks of aging. Molecules, 21(2), 163. PMID: 26840281 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273542 reference] DOI: 10.3390/molecules21020163</ref> Olive oil is rich in monounsaturated oleic acid and phenolic compounds, as well as squalene. The capacity of olive oil to stop or slow down the inflammatory processes linked to chronic degenerative disorders also supports its role as an anti-atherosclerotic, therefore improving the lipid profile. The phenolic components of olive oil, such as luteolin, apigenin, ferulic, coumaric acid, or caffeic acid, have antibacterial effects and promote the regeneration of fibroblasts.<ref>Melguizo-Rodríguez, L., Illescas-Montes, R., Costela-Ruiz, V. J., Ramos-Torrecillas, J., de Luna-Bertos, E., García-Martínez, O., & Ruiz, C. (2021). Antimicrobial properties of olive oil phenolic compounds and their regenerative capacity towards fibroblast cells. Journal of Tissue Viability, 30(3), 372-378. PMID: 33810929 DOI:[https://doi.org/10.1016/j.jtv.2021.03.003 reference]</ref>		One of the most examined oils for its health properties is olive oil, especially extra virgin olive oil (EVOO).<ref>Riolo, R., De Rosa, R., Simonetta, I., & Tuttolomondo, A. (2022). Olive Oil in the Mediterranean Diet and Its Biochemical and Molecular Effects on Cardiovascular Health through an Analysis of Genetics and Epigenetics. International Journal of Molecular Sciences, 23(24), 16002. PMID: 36555645 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782563 reference] DOI: 10.3390/ijms232416002</ref><ref>Fernández del Río, L., Gutiérrez-Casado, E., Varela-López, A., & Villalba, J. M. (2016). Olive oil and the hallmarks of aging. Molecules, 21(2), 163. PMID: 26840281 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273542 reference] DOI: 10.3390/molecules21020163</ref> Olive oil is rich in monounsaturated oleic acid and phenolic compounds, as well as squalene. The capacity of olive oil to stop or slow down the inflammatory processes linked to chronic degenerative disorders also supports its role as an anti-atherosclerotic, therefore improving the lipid profile. The phenolic components of olive oil, such as luteolin, apigenin, ferulic, coumaric acid, or caffeic acid, have antibacterial effects and promote the regeneration of fibroblasts.<ref>Melguizo-Rodríguez, L., Illescas-Montes, R., Costela-Ruiz, V. J., Ramos-Torrecillas, J., de Luna-Bertos, E., García-Martínez, O., & Ruiz, C. (2021). Antimicrobial properties of olive oil phenolic compounds and their regenerative capacity towards fibroblast cells. Journal of Tissue Viability, 30(3), 372-378. PMID: 33810929 DOI:[https://doi.org/10.1016/j.jtv.2021.03.003 reference]</ref>
			The lipid fraction constituting about 98% of the olive oil composition and comprised of fatty acids (mainly in the form of triglycerides) such as oleic acid (monounsaturated omega-9 fatty acid accounting for about 55% and up to 83% of the total fatty acid content of the olive oil, depending on the reference cultivar and on the extraction techniques), linoleic acid (omega-6 polyunsaturated fatty acid accounting for 3–21% of the total fatty acid content of the olive oil), α-linolenic acid (omega-3 polyunsaturated fatty acid accounting for less than 1% of the total fatty acid content of the olive oil), and palmitic acid (long-chain saturated fatty acid accounting for 10–23% of the total fatty acid content of the olive oil). <ref name="EVOO" >Infante, R., Infante, M., Pastore, D., Pacifici, F., Chiereghin, F., Malatesta, G., ... & Della-Morte, D. (2023). An Appraisal of the Oleocanthal-Rich Extra Virgin Olive Oil (EVOO) and Its Potential Anticancer and Neuroprotective Properties. International Journal of Molecular Sciences, 24(24), 17323. PMID: 38139152 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10744258/ PMC10744258] DOI: 10.3390/ijms242417323</ref> The set of secondary metabolites (constituting about 1–2% of the Extra Virgin Olive Oil (EVOO) composition) is generally defined as that of the “minor compounds,” such as phenolic compounds and lipophilic compounds (like α-tocopherol or vitamin E). Hydrophilic phenolic compounds present in EVOO belong to different classes: secoiridoids, phenolic acids, phenolic alcohols, lignans and flavonoids.<ref name="EVOO" /> For the extra virgin olive oil quality index the most relevant approach is to select the concentrations of seven selected phenols, namely: gallic acid, β-tocopherol, oleuropein aglycone, ligstroside aglycone, oleacein, hydroxytyrosol and apigenin.<ref>Różańska, A., Russo, M., Cacciola, F., Salafia, F., Polkowska, Ż., Dugo, P., & Mondello, L. (2020). Concentration of potentially bioactive compounds in Italian extra virgin olive oils from various sources by using LC-MS and multivariate data analysis. Foods, 9(8), 1120.
			PMID: 32823794 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466375/ PMC7466375] DOI: 10.3390/foods9081120</ref>

	== Tomatoes in the Mediterranean Diet ==		== Tomatoes in the Mediterranean Diet ==

Dmitry Dzhagarov: /* Tomatoes in the Mediterranean Diet */

2023-08-21T07:33:54Z

Tomatoes in the Mediterranean Diet

← Older revision		Revision as of 07:33, 21 August 2023
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	Like [[metformin]], naringenin displays in vitro and in vivo antidiabetic effects by sensitizing [[FOXO longevity genes\|insulin signaling]] in insulin-sensitive cells and tissues, inhibiting gluconeogenesis in hepatocytes, suppressing adipocyte proliferation and adipogenesis, and protecting pancreas β-cells from apoptosis.<ref>Nyane, N. A., Tlaila, T. B., Malefane, T. G., Ndwandwe, D. E., & Owira, P. M. O. (2017). Metformin-like antidiabetic, cardio-protective and non-glycemic effects of naringenin: Molecular and pharmacological insights. European Journal of Pharmacology, 803, 103-111. PMID: 28322845 DOI:[https://doi.org/10.1016/j.ejphar.2017.03.042 reference]</ref> Antioxidant activity of naringenin may be related to its upregulation through a transcriptional mechanism of intracellular [[Heat-shock response\|heat shock]] protein 70 (HSP70), by which '''naringenin improves diabetic- or hyperglycemia-induced impairment of endothelial function'''.<ref>Zhang, Z., Liu, H., Hu, X., He, Y., Li, L., Yang, X., ... & Tao, S. (2022). Heat Shock Protein 70 Mediates the Protective Effect of Naringenin on High-Glucose-Induced Alterations of Endothelial Function. International Journal of Endocrinology, 2022:7275765 PMID: 35958293 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359828 reference] DOI: 10.1155/2022/7275765</ref>		Like [[metformin]], naringenin displays in vitro and in vivo antidiabetic effects by sensitizing [[FOXO longevity genes\|insulin signaling]] in insulin-sensitive cells and tissues, inhibiting gluconeogenesis in hepatocytes, suppressing adipocyte proliferation and adipogenesis, and protecting pancreas β-cells from apoptosis.<ref>Nyane, N. A., Tlaila, T. B., Malefane, T. G., Ndwandwe, D. E., & Owira, P. M. O. (2017). Metformin-like antidiabetic, cardio-protective and non-glycemic effects of naringenin: Molecular and pharmacological insights. European Journal of Pharmacology, 803, 103-111. PMID: 28322845 DOI:[https://doi.org/10.1016/j.ejphar.2017.03.042 reference]</ref> Antioxidant activity of naringenin may be related to its upregulation through a transcriptional mechanism of intracellular [[Heat-shock response\|heat shock]] protein 70 (HSP70), by which '''naringenin improves diabetic- or hyperglycemia-induced impairment of endothelial function'''.<ref>Zhang, Z., Liu, H., Hu, X., He, Y., Li, L., Yang, X., ... & Tao, S. (2022). Heat Shock Protein 70 Mediates the Protective Effect of Naringenin on High-Glucose-Induced Alterations of Endothelial Function. International Journal of Endocrinology, 2022:7275765 PMID: 35958293 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359828 reference] DOI: 10.1155/2022/7275765</ref>

			== The Mediterranean Lifestyle ==
			There is already robust evidence supporting the cardiometabolic health benefits of the traditional Mediterranean diet, rich in colourful fruits, vegetables, olive oil, edible wild greens, whole grains, seafood, and protein such as, fermented dairy products; whereas less information is available on the potential synergistic effects of a general healthy lifestyle.<ref>Christodoulou, E., Deligiannidou, G. E., Kontogiorgis, C., Giaginis, C., & Koutelidakis, A. E. (2023). Natural Functional Foods as a Part of the Mediterranean Lifestyle and Their Association with Psychological Resilience and Other Health-Related Parameters. Applied Sciences, 13(7), 4076. https://doi.org/10.3390/app13074076</ref> Other individual components such as for example, reducing sedentary behavior and increasing physical activity, sleep duration, taking naps, regular cheerful connection and communication with people, limiting salt and sugar intake—are also known to have positive effects on cardiometabolic health.<ref>Romero‐Cabrera, J. L., García‐Ríos, A., Sotos‐Prieto, M., Quintana‐Navarro, G., Alcalá‐Díaz, J. F., Martín‐Piedra, L., ... & Pérez‐Martínez, P. (2023). Adherence to a Mediterranean lifestyle improves metabolic status in coronary heart disease patients: A prospective analysis from the CORDIOPREV study. Journal of Internal Medicine, 293(5), 574-588. PMID: 36585892 DOI: 10.1111/joim.13602</ref><ref>Maroto-Rodriguez, J., Delgado-Velandia, M., Ortolá, R., Perez-Cornago, A., Kales, S. N., Rodríguez-Artalejo, F., & Sotos-Prieto, M. (2023, August). Association of a Mediterranean Lifestyle With All-Cause and Cause-Specific Mortality: A Prospective Study from the UK Biobank. In Mayo Clinic Proceedings. Elsevier. https://doi.org/10.1016/j.mayocp.2023.05.031</ref>

	== References ==		== References ==

Dmitry Dzhagarov: /* Heath benefits of the Mediterranean Diet */

2023-04-10T16:58:18Z

Heath benefits of the Mediterranean Diet

← Older revision		Revision as of 16:58, 10 April 2023
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	Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>		Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>
	Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>		Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>
	Adherence to Mediterranean diet is inversely associated with risk of frailty and pre-frailty in older adults and especially elders above 65 years old.<ref>Poursalehi, D., Lotfi, K., & Saneei, P. (2023). Adherence to the Mediterranean diet and risk of frailty and pre-frailty in elderly adults: A systematic review and dose-response meta-analysis with GRADE assessment. Ageing Research Reviews, 87, 101903. PMID: 36871780 DOI:[https://doi.org/10.1016/j.arr.2023.101903 10.1016/j.arr.2023.101903] </ref>		Adherence to Mediterranean diet is inversely associated with risk of [[frailty]] and pre-frailty in older adults and especially elders above 65 years old.<ref>Poursalehi, D., Lotfi, K., & Saneei, P. (2023). Adherence to the Mediterranean diet and risk of frailty and pre-frailty in elderly adults: A systematic review and dose-response meta-analysis with GRADE assessment. Ageing Research Reviews, 87, 101903. PMID: 36871780 DOI:[https://doi.org/10.1016/j.arr.2023.101903 10.1016/j.arr.2023.101903] </ref>

	== Olive Oil in the Mediterranean Diet ==		== Olive Oil in the Mediterranean Diet ==

Dmitry Dzhagarov: /* Heath benefits of the Mediterranean Diet */

2023-04-10T16:56:37Z

Heath benefits of the Mediterranean Diet

← Older revision		Revision as of 16:56, 10 April 2023
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	Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>		Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>
	Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>		Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>
			Adherence to Mediterranean diet is inversely associated with risk of frailty and pre-frailty in older adults and especially elders above 65 years old.<ref>Poursalehi, D., Lotfi, K., & Saneei, P. (2023). Adherence to the Mediterranean diet and risk of frailty and pre-frailty in elderly adults: A systematic review and dose-response meta-analysis with GRADE assessment. Ageing Research Reviews, 87, 101903. PMID: 36871780 DOI:[https://doi.org/10.1016/j.arr.2023.101903 10.1016/j.arr.2023.101903] </ref>

	== Olive Oil in the Mediterranean Diet ==		== Olive Oil in the Mediterranean Diet ==

Dmitry Dzhagarov: /* Heath benefits of the Mediterranean Diet */

2023-04-02T19:52:49Z

Heath benefits of the Mediterranean Diet

← Older revision		Revision as of 19:52, 2 April 2023
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	Several randomized controlled trials have showed the positive effects of the MedDiet style on several cardiovascular risk factors, such as body mass index, waist circumference, blood lipids, blood pressure, inflammatory markers and adhesion molecules, and diabetes and how these advantages of the MeDi are maintained in comparison of a low-fat diet. Some studies reported a positive effect of adherence to a Mediterranean Diet and heart failure incidence, whereas some studies showed that the incidence of major cardiovascular events was lower among those assigned to MedDiet supplemented with extra-virgin olive oil or nuts than among those assigned to a reduced-fat diet.<ref>Tuttolomondo, A., Simonetta, I., Daidone, M., Mogavero, A., Ortello, A., & Pinto, A. (2019). Metabolic and vascular effect of the Mediterranean diet. International journal of molecular sciences, 20(19), 4716. PMID: 31547615 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801699 reference] DOI: 10.3390/ijms20194716</ref>		Several randomized controlled trials have showed the positive effects of the MedDiet style on several cardiovascular risk factors, such as body mass index, waist circumference, blood lipids, blood pressure, inflammatory markers and adhesion molecules, and diabetes and how these advantages of the MeDi are maintained in comparison of a low-fat diet. Some studies reported a positive effect of adherence to a Mediterranean Diet and heart failure incidence, whereas some studies showed that the incidence of major cardiovascular events was lower among those assigned to MedDiet supplemented with extra-virgin olive oil or nuts than among those assigned to a reduced-fat diet.<ref>Tuttolomondo, A., Simonetta, I., Daidone, M., Mogavero, A., Ortello, A., & Pinto, A. (2019). Metabolic and vascular effect of the Mediterranean diet. International journal of molecular sciences, 20(19), 4716. PMID: 31547615 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801699 reference] DOI: 10.3390/ijms20194716</ref>

			Mediterranean diet adherence had, in general, a positive role in muscle mass and muscle function with a lower risk of sarcopenia.<ref>Papadopoulou, S. K., Detopoulou, P., Voulgaridou, G., Tsoumana, D., Spanoudaki, M., Sadikou, F., ... & Nikolaidis, P. (2023). Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review. Nutrients, 15(5), 1104. PMID: 36904104 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005300 reference] DOI: 10.3390/nu15051104</ref><ref>Cacciatore, S., Calvani, R., Marzetti, E., Picca, A., Coelho-Júnior, H. J., Martone, A. M., ... & Landi, F. (2023). Low Adherence to Mediterranean Diet Is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Results from the Longevity Check-Up (Lookup) 7+ Project. Nutrients, 15(4), 1026. PMID: 36839385 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959184 reference] DOI: 10.3390/nu15041026</ref>
			Adherence to the MedDiet was inversely related to type 2 diabetes risk in a dose-response manner.<ref>Zeraattalab-Motlagh, S., Jayedi, A., & Shab-Bidar, S. (2022). Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies. European journal of nutrition, 1-14. PMID: 35001218 DOI: 10.1007/s00394-021-02761-3</ref><ref>Sarsangi, P., Salehi-Abargouei, A., Ebrahimpour-Koujan, S., & Esmaillzadeh, A. (2022). Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies. Advances in Nutrition, 13(5), 1787-1798. PMID: 35472102 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526848 reference] DOI: 10.1093/advances/nmac046</ref>
	Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>		Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMC[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012551/ 10012551] DOI: 10.1186/s12916-023-02772-3</ref>

Dmitry Dzhagarov at 19:04, 2 April 2023

2023-04-02T19:04:25Z

Show changes

Dmitry Dzhagarov: /* Heath benefits of the Mediterranean Diet */

2023-04-02T18:46:39Z

Heath benefits of the Mediterranean Diet

← Older revision		Revision as of 18:46, 2 April 2023
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	Several randomized controlled trials have showed the positive effects of the MedDiet style on several cardiovascular risk factors, such as body mass index, waist circumference, blood lipids, blood pressure, inflammatory markers and adhesion molecules, and diabetes and how these advantages of the MeDi are maintained in comparison of a low-fat diet. Some studies reported a positive effect of adherence to a Mediterranean Diet and heart failure incidence, whereas some studies showed that the incidence of major cardiovascular events was lower among those assigned to MedDiet supplemented with extra-virgin olive oil or nuts than among those assigned to a reduced-fat diet.<ref>Tuttolomondo, A., Simonetta, I., Daidone, M., Mogavero, A., Ortello, A., & Pinto, A. (2019). Metabolic and vascular effect of the Mediterranean diet. International journal of molecular sciences, 20(19), 4716. PMID: 31547615 PMCID: PMC6801699 DOI: 10.3390/ijms20194716</ref>		Several randomized controlled trials have showed the positive effects of the MedDiet style on several cardiovascular risk factors, such as body mass index, waist circumference, blood lipids, blood pressure, inflammatory markers and adhesion molecules, and diabetes and how these advantages of the MeDi are maintained in comparison of a low-fat diet. Some studies reported a positive effect of adherence to a Mediterranean Diet and heart failure incidence, whereas some studies showed that the incidence of major cardiovascular events was lower among those assigned to MedDiet supplemented with extra-virgin olive oil or nuts than among those assigned to a reduced-fat diet.<ref>Tuttolomondo, A., Simonetta, I., Daidone, M., Mogavero, A., Ortello, A., & Pinto, A. (2019). Metabolic and vascular effect of the Mediterranean diet. International journal of molecular sciences, 20(19), 4716. PMID: 31547615 PMCID: PMC6801699 DOI: 10.3390/ijms20194716</ref>

			Higher adherence to a MedDiet was also associated with lower dementia risk, independent of genetic risk, underlining the importance of diet in dementia prevention interventions.<ref>Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., ... & Stevenson, E. (2023). Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC medicine, 21(1), 1-13. PMID: 36915130 PMCID: PMC10012551 DOI: 10.1186/s12916-023-02772-3</ref>

	== Olive Oil in the Mediterranean Diet ==		== Olive Oil in the Mediterranean Diet ==

Andrea at 12:21, 26 March 2023

2023-03-26T12:21:14Z

← Older revision		Revision as of 12:21, 26 March 2023
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	[[Category:Main list]]		[[Category:Main list]]
	[[Category:Lifespan interventions]]		[[Category:Lifespan interventions]]
	~~[[Category:Drafts]]~~

Andrea at 12:20, 26 March 2023

2023-03-26T12:20:18Z

Show changes