https://en.longevitywiki.org/wiki/Proteostasis/history?feed=atom
Proteostasis - Revision history
2026-04-08T12:43:21Z
Revision history for this page on the wiki
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https://en.longevitywiki.org/index.php?title=Proteostasis&diff=2355&oldid=prev
Andrea: category change
2022-12-27T13:01:47Z
<p>category change</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:01, 27 December 2022</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Loss of proteostasis is considered to be a [[Hallmarks of aging|hallmark of aging]],<ref>López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. ''Cell'', ''153''(6), 1194-1217.</ref> and several ubiquitin-dependent protein degradation pathways have been shown to regulate lifespan.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Loss of proteostasis is considered to be a [[Hallmarks of aging|hallmark of aging]],<ref>López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. ''Cell'', ''153''(6), 1194-1217.</ref> and several ubiquitin-dependent protein degradation pathways have been shown to regulate lifespan.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category:<del style="font-weight: bold; text-decoration: none;">Longevity</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><references /></ins></div></td></tr>
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Andrea
https://en.longevitywiki.org/index.php?title=Proteostasis&diff=2199&oldid=prev
Andrea: new entry in progress
2022-12-01T16:59:01Z
<p>new entry in progress</p>
<p><b>New page</b></p><div>{{Draft-article}}<br />
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Proteostasis refers to the rate or turnover of synthesis and degradation ([[proteolysis]]) of misfolded and damaged proteins. Proteostasis helps maintain cellular and protein homeostasis and is regulated by the ubiquitin/proteasome system (UPS).<ref>Hoppe T. Life and destruction: ubiquitin-mediated proteolysis in aging and longevity. F1000 Biol Rep. 2010 Nov 11;2:79. doi: 10.3410/B2-79. PMID: 21151840; PMCID: PMC2998811.</ref> <br />
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Loss of proteostasis is considered to be a [[Hallmarks of aging|hallmark of aging]],<ref>López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. ''Cell'', ''153''(6), 1194-1217.</ref> and several ubiquitin-dependent protein degradation pathways have been shown to regulate lifespan.<br />
[[Category:Longevity]]</div>
Andrea