CVH metrics and quality of life

From Longevity Wiki

Numerous epidemiological studies have shown that achievement of a greater number of ideal CVH (cardiovascular health) metrics is associated with lower incidences of cardiovascular diseases (CVDs) and stroke, cardiovascular mortality, and all-cause mortality.[1] Better CVH has also been associated with lower risks for cancer, dementia, end-stage renal disease, and chronic obstructive pulmonary disease; better cognitive function and quality of life; compression of morbidity (longer health span); and lower health care costs despite a longer life span, among many other positive outcomes.[2][3][4] CVH characterized by 7 health behaviors and health factors called the Life’s Simple 7 (LS7) metrics[5] and modifying CVH—now called Life’s Essential 8 (LE8) after the inclusion of sleep as a new CVH component—to catalyze ongoing efforts to improve CVH in all individuals and the population.[6]

Adapted with modification from Michos & Khan., 2021[7][8]
CVH metrics CVH metrics Point Definition
Smoking 0 Current smoker
1 Former smoker, quit ≤12 months ago
2 Never smoker or quit >12 months ago
Body Mass Index 0 ≥30 kg/m2
1 25.0–29.99 kg/m2
2 <25.0 kg/m2 0
Physical Activity 0 No exercise
1 1–149 min of moderate exercise or 1–74 min of vigorous exercise/week
2 150+ min of moderate exercise or 75+ min of vigorous exercise/week
Diet 0 0–1 components of healthy diet
1 2–3 components of healthy diet
2 4–5 components of healthy diet
Total Cholesterol 0 ≥240 mg/dL
1 200–239 mg/dL or treated to <200mg/dL
2 <200 mg/dL, unmedicated
Blood Pressure 0 SBP ≥140 mmHg or DBP ≥90 mmHg
1 SBP 120–139 mmHg or DBP 80–89 mmHg or treated to <120/80 mm Hg
2 <120/80 mm Hg, unmedicated
Blood Glucose 0 ≥126 mg/dL fasting
1 100–125 mg/dL fasting or treated to <100 mg/dL
2 <100 mg/dL fasting, unmedicated
Sleep 0 not feeling rested even after getting enough sleep, repeatedly waking up during the night, and experiencing symptoms of sleep disorders (such as snoring or gasping for air)
1 6–7 hours occasionally waking up during the night
2 (18 to 60 years) 7–9 hours (65 years and older) 7–8 hours, with good sleep quality, unmedicated


  1. Zhang, R., Wu, M., Zhang, W., Liu, X., Pu, J., Wei, T., ... & Lv, Y. (2023). Association between life’s essential 8 and biological ageing among US adults. Journal of Translational Medicine, 21(1), 1-12. PMID: 37710295 PMC10503107 DOI: 10.1186/s12967-023-04495-8
  2. Wang, X., Ma, H., Li, X., Heianza, Y., Manson, J. E., Franco, O. H., & Qi, L. (2023). Association of cardiovascular health with life expectancy free of cardiovascular disease, diabetes, cancer, and dementia in UK adults. JAMA Internal Medicine, 183(4), 340-349. PMID: 36848126 PMC9972243 (available on 2024-02-27) DOI: 10.1001/jamainternmed.2023.0015
  3. Ma, H., Wang, X., Xue, Q., Li, X., Liang, Z., Heianza, Y., ... & Qi, L. (2023). Cardiovascular Health and Life Expectancy Among Adults in the United States. Circulation, 147(15), 1137-1146. PMID: 37036905 PMC10165723 (available on 2024-04-11) DOI: 10.1161/CIRCULATIONAHA.122.062457
  4. Rasmussen-Torvik, L. J., Shay, C. M., Abramson, J. G., Friedrich, C. A., Nettleton, J. A., Prizment, A. E., & Folsom, A. R. (2013). Ideal cardiovascular health is inversely associated with incident cancer: the Atherosclerosis Risk In Communities study. Circulation, 127(12), 1270-1275. PMID: 23509058 PMC3685848 DOI: 10.1161/CIRCULATIONAHA.112.001183
  5. Lloyd-Jones, D. M., Hong, Y., Labarthe, D., Mozaffarian, D., Appel, L. J., Van Horn, L., ... & Rosamond, W. D. (2010). Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association’s strategic Impact Goal through 2020 and beyond. Circulation, 121(4), 586-613.
  6. PMID: 37710295 PMC10503107 DOI: 10.1186/s12967-023-04495-8
  7. Michos, E. D., & Khan, S. S. (2021). Further understanding of ideal cardiovascular health score metrics and cardiovascular disease. Expert review of cardiovascular therapy, 19(7), 607-617. PMID: 34053373 PMC8338780 DOI: 10.1080/14779072.2021.1937127
  8. Radovanovic, M., Jankovic, J., Mandic-Rajcevic, S., Dumic, I., Hanna, R. D., & Nordstrom, C. W. (2023). Ideal Cardiovascular Health and Risk of Cardiovascular Events or Mortality: A Systematic Review and Meta-Analysis of Prospective Studies. Journal of Clinical Medicine, 12(13), 4417. PMID: 37445451 PMC10342759 DOI: 10.3390/jcm12134417