PRC2-AgeIndex

From Longevity Wiki

PRC2-AgeIndex is the average DNA methylation (DNAm) in Polycomb Repressive Complex 2 (PRC2) low-methylated regions (LMRs) which are highly bound by PRC2.[1] PRC2-AgeIndex is a universal biomarker of cellular aging in somatic cells.[1]

  1. 1.0 1.1 Moqri, M., Cipriano, A., Simpson, D.J. et al. (2024). PRC2-AgeIndex as a universal biomarker of aging and rejuvenation. Nat Commun 15, 5956 https://doi.org/10.1038/s41467-024-50098-2