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Extracellular vesicles (EVs) propagate the state of their source cell. As cells become senescent or enter a damaged state, EV secretion increases. EVs secreted by these unhealthy cells may induce inflammation or damage responses in the recipient cells, eventually inducing a similar unhealthy state in these cells. In contrast, EVs secreted by healthy tissue provide trophic support and promote the maintenance of homeostasis in recipient cells.

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current13:28, 14 March 2023Thumbnail for version as of 13:28, 14 March 2023913 × 713 (112 KB)Dmitry Dzhagarov (talk | contribs)

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