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...sphate groups. One nucleotide contains an adenine nucleobase and the other nicotinamide.]] ...hate groups. One nucleotide contains an adenine nucleobase and the other a nicotinamide. It serves both as a critical '''coenzyme''' for enzymes that fuel reductio ...

...]] activity, [[NAD+]] content, and NAD⁺/NADH ratio by targeting nicotinamide phosphoribosyl-transferase ([[NAD+#NAMPT|NAMPT]]).<ref>Pi, C., Ma, C., Wang fibroblasts (HDFs), and induced cellular senescence.<ref>Hong, J. Y., Nam, H. J., Ji, H., Kim, Y. Y., Hyun, M., Park, H. J., ... & McCrea, P. D. (202 ...