Role of JNK in aging: Revision history

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21 September 2024

  • curprev 10:3410:34, 21 September 2024Dmitry Dzhagarov talk contribs 1,811 bytes +1,811 Created page with "'''JNK (c-Jun N-terminal kinase)''' is a crucial signaling pathway that plays a significant role in normal physiological processes. The JNK signaling pathway exhibits a dual nature during the aging process. For instance, when JNK is activated in the brain, it leads to a prolonged lifespan, whereas moderate activation of JNK in midgut intestinal stem cells (ISCs) and enteroblasts significantly shortens lifespan.<ref>Gan, T., Fan, L., Zhao, L., Misra, M., Liu, M., Zhang, M..."