Non-Genomic Hallmarks of Aging
From Longevity Wiki
The hallmarks of aging can be divided into genomic hallmarks (closely related to DNA) and non-genomic hallmarks. Genomic hallmarks include genomic instability, telomere attrition and epigenetic alterations. Non-genomic hallmarks include cellular senescence, loss of proteostasis, deregulated nutrient sensing, altered intercellular communication, immune system dysfunction and chronic inflammation, stem cell exhaustion, mitochondrial dysfunction and dysbiosis.[1]
Senescence
Proteostasis
Deregulated Nutrient Sensing
Intercellular Communication
Immune System Dysfunction
Stem Cell Exhaustion
Mitochondrial Dysfunctions
Dysbiosis
- ↑ Holmannova, D., Borsky, P., Parova, H., Stverakova, T., Vosmik, M., Hruska, L., ... & Borska, L. (2023). Non-Genomic Hallmarks of Aging—The Review. International Journal of Molecular Sciences, 24(20), 15468. https://doi.org/10.3390/ijms242015468