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From Longevity Wiki
  • Albumin blood tests can test the function of liver and kidney. Generally, albumin levels peak at 20 years old and then decrease with age. ...58, Oct. 1996</ref> It is also a key indicator of chronic kidney and liver disease. ...
    8 KB (1,085 words) - 15:27, 22 March 2023
  • ...-02296-6 10.1038/s41591-023-02296-6]</ref> Organ age gaps (columns) for 16 disease categories (rows), compared to healthy individuals (HC). Distributions colo Abbreviations: chronic obstructive pulmonary disease (COPD), chronic kidney disease (CKD), brain gray matter (GM), brain white matter (WM), brain functional co ...
    6 KB (828 words) - 07:09, 19 May 2023
  • ...SAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney. Biochemical and biophysical research communications, 316(2), 490-500. PMID ..., J. (2021). Uterine sensitization-associated gene-1 in the progression of kidney diseases. Journal of Immunology Research, 2021, 1-6. PMID: 34414243 PMC8369 ...
    9 KB (1,260 words) - 16:46, 12 July 2023
  • ...(CML), of which most<u><ref>https://www.cancerresearchuk.org/about-cancer/chronic-myeloid-leukaemia-cml/about</ref></u> have a so-called ''Philadelphia chrom ...ber of senescent cells in the body fat of individuals with diabetic kidney disease<ref name=":3" /><ref>https://www.thelancet.com/journals/ebiom/article/PIIS2 ...
    10 KB (1,484 words) - 15:13, 16 October 2023
  • ...H. N., Gupta, R. C., Kohli, S., Wang, M., Hachem, S., & Zhang, K. (2016). Chronic therapy with elamipretide (MTP-131), a novel mitochondria-targeting peptide ...tochondrial health and myocardial structural remodeling in metabolic heart disease, aging, and heart failure. The journal of cardiovascular aging, 3(1). PMID: ...
    8 KB (1,039 words) - 12:26, 29 March 2023
  • ...h age in several tissues, including adipose (fat) tissue, skeletal muscle, kidney tissue, and skin.<ref>Herbig, U., Ferreira, M., Condel, L., Carey, D., & Se ...ment of chronic lung conditions like asthma, chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis (IPF). Two days following a fiset ...
    12 KB (1,725 words) - 18:50, 15 April 2023
  • ...on or in the regulation of cell growth. Cancer is a well-known age-related disease, with most cancer sufferers being of older age. ...ef name=":7">Laconi, E., Marongiu, F., & DeGregori, J. (2020). Cancer as a disease of old age: changing mutational and microenvironmental landscapes. ''Britis ...
    18 KB (2,737 words) - 10:26, 26 September 2023
  • ...ef name=":0">Oeseburg, Hisko, m.fl. ”Telomere Biology in Healthy Aging and Disease”. ''Pflügers Archiv - European Journal of Physiology'', vol. 459, nr 2, jan ...icacy and safety of GV1001 in patients with moderate-to-severe Alzheimer’s disease already receiving donepezil: A phase 2 randomized, double-blind, placebo-co ...
    16 KB (2,310 words) - 18:51, 16 February 2024
  • Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). == COVID-19 as a disease of aging == ...
    37 KB (5,360 words) - 08:50, 28 December 2022
  • ...mong others, is a medication which is used in the treatment of Parkinson's disease and major depressive disorder. For basic information, see '''Wikipedia'''. ...www.sciencedirect.com/science/article/abs/pii/S0197458097000092?via%3Dihub Chronic Treatment of Syrian Hamsters With Low-Dose Selegiline Increases Life Span i ...
    15 KB (2,013 words) - 19:50, 15 September 2023
  • ...has an immunosuppressant function that is used in preventing rejection of kidney transplants by the immune system. It is also used to coat coronary stents, ...& Kaeberlein, M. (2013). mTOR is a key modulator of ageing and age-related disease. ''Nature'', ''493''(7432), 338-345.</ref><ref>Mannick, J. B., & Lamming, D ...
    47 KB (6,761 words) - 18:05, 7 December 2023
  • ...research towards the cure of age-related diseases (e.g. Alzheimer’s, heart disease, and [[Aging and Cancer|most cancers]]) – a desire present at every level o ...f time, and that aging is an entirely separate category from ''age-related disease.''<ref>Sierra, F. (2016). The emergence of geroscience as an interdisciplin ...
    62 KB (9,146 words) - 20:56, 10 May 2023
  • ...ting Scale, and lower odds of having gastrointestinal, dental, orthopedic, kidney, urinary, liver and pancreas disorders. The authors suggest that while this The Restrikal study, initiated in 2006, studied the effect of chronic 30% CR in the grey mouse lemur primate, ''Microcebus murinus''.<ref name=": ...
    43 KB (6,182 words) - 07:21, 14 December 2023
  • ...[[Diabetes mellitus type 2|diabetes]], and [[Chronic kidney disease|kidney disease]], ultimately [[Causes of death by rate|leading to death]]. ...(2020). A senescence-centric view of aging: implications for longevity and disease. Trends in Cell Biology, 30(10), 777-791. PMID: 32800659 DOI:[https://doi. ...
    108 KB (15,002 words) - 07:29, 7 April 2024